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CyFlow™ ABRA1 Purified

CyFlow™ ABRA1 Purified
Application: Flow cytometry, Immunoprecipitation, Western blot
Clonality: monoclonal
Target Species: Human
Regulatory Status: RUO
Source Species: Mouse
Format/Fluorochrome: Purified
Isotype: IgG
Antigen: ABRA1
Clone: ABRA1-01
Field of Interest: Adaptor proteins, Transcription
Order number: AP667270
267,00  EUR *

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Concentration Unit mg/mL Concentration 1 Quantity 0.1 mg Volume 0.1 mL... more
Product information "CyFlow™ ABRA1 Purified"
Application: Flow cytometry, Immunoprecipitation, Western blot
Clonality: monoclonal
Target Species: Human
Regulatory Status: RUO
Source Species: Mouse
Format/Fluorochrome: Purified
Isotype: IgG
Antigen: ABRA1
Clone: ABRA1-01
Field of Interest: Adaptor proteins, Transcription

Concentration Unitmg/mL
Concentration1
Quantity0.1 mg
Volume0.1 mL
ImmunogenRecombinant protein corresponding to amino acids 1-313 of ABRA1 with N-terminal His6 tag
Background InformationABRA1 (Abraxas, CCDC98) is an adaptor protein that is essential for formation and function of BRCA1 A tumor suppressor complex. This complex plays critical roles in DNA repair, cell cycle checkpoint control, and maintenance of genomic stability. ABRA1 mediates interaction of ubiquitin-interacting motif-containing protein RAP80 and deubiquitination enzyme BRCC36 with BRCA1/BARD1. ABRA1 controls both DNA-damage-induced formation of BRCA1 foci and BRCA1-dependent G2/M checkpoint activation.
Storage BufferThe reagent is provided in phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide.
StorageAvoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
StabilityDo not use after expiration date stamped on vial label.